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Evaluation and prediction of slope stability using machine learning approaches

《结构与土木工程前沿（英文）》 2021年第15卷第4期页码 821-833 doi: 10.1007/s11709-021-0742-8

摘要： In this paper, the machine learning (ML) model is built for slope stability evaluation and meets the high precision and rapidity requirements in slope engineering. Different ML methods for the factor of safety (FOS) prediction are studied and compared hoping to make the best use of the large variety of existing statistical and ML regression methods collected. The data set of this study includes six characteristics, namely unit weight, cohesion, internal friction angle, slope angle, slope height, and pore water pressure ratio. The whole ML model is primarily divided into data preprocessing, outlier processing, and model evaluation. In the data preprocessing, the duplicated data are first removed, then the outliers are filtered by the LocalOutlierFactor method and finally, the data are standardized. 11 ML methods are evaluated for their ability to learn the FOS based on different input parameter combinations. By analyzing the evaluation indicators R ², MAE, and MSE of these methods, SVM, GBR, and Bagging are considered to be the best regression methods. The performance and reliability of the nonlinear regression method are slightly better than that of the linear regression method. Also, the SVM-poly method is used to analyze the susceptibility of slope parameters.

关键词： slope stability factor of safety regression machine learning repeated cross-validation

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The adoption of repeated measurement of variance analysis and Shapiro–Wilk test

《医学前沿（英文）》 2022年第16卷第4期页码 659-660 doi: 10.1007/s11684-021-0908-8

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Answer for questions of repeated measurements of variance analysis and distribution test of data — Authors

《医学前沿（英文）》 2022年第16卷第4期页码 661-664 doi: 10.1007/s11684-021-0907-9

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Crushed rocks stabilized with organosilane and lignosulfonate in pavement unbound layers: Repeated load

Diego Maria BARBIERI, Inge HOFF, Chun-Hsing HO

《结构与土木工程前沿（英文）》 2021年第15卷第2期页码 412-424 doi: 10.1007/s11709-021-0700-5

摘要： The creation of the new “Ferry-Free Coastal Highway Route E39” in southwest Norway entails the production of a remarkable quantity of crushed rocks. These resources could be beneficially employed as aggregates in the unbound courses of the highway itself or other road pavements present nearby. Two innovative stabilizing agents, organosilane and lignosulfonate, can significantly enhance the key properties, namely, resilient modulus and resistance against permanent deformation, of the aggregates that are excessively weak in their natural state. The beneficial effect offered by the additives was thoroughly evaluated by performing repeated load triaxial tests. The study adopted the most common numerical models to describe these two key mechanical properties. The increase in the resilient modulus and reduction in the accumulated vertical permanent deformation show the beneficial impact of the additives. Furthermore, a finite element model was created to simulate the repeated load triaxial test by implementing nonlinear elastic and plastic constitutive relationships.

关键词： organosilane lignosulfonate crushed rocks pavement unbound layers repeated load triaxial test finite element analysis

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Effect of repeated gonadotropin stimulation on ovarian reserves and proliferation of ovarian surface

Linlin LIANG, Bei XU, Guijin ZHU

《医学前沿（英文）》 2009年第3卷第2期页码 220-226 doi: 10.1007/s11684-009-0037-2

摘要： This study aimed to evaluate the effect of repeated ovarian stimulation (OS) on the ovarian follicular population and morphology in female mice and its influence on the embryo’s developmental ability, and the profile of the ovarian surface epithelium (OSE). A total of 75 mice were enrolled in this experiment and randomly assigned into three groups: repeated ovarian stimulated group [ =25; receiving 5 IU pregnant mare serum gonadotrophin (PMSG) and human chorionic gonadotropin (hCG) at 6 day intervals for 5 cycles]; single ovarian stimulated group ( =25; receiving 5 IU PMSG and hCG for 1 cycle), and control group ( =25; without additional treatment). The follicle number at various stages and the morphologies were recorded respectively in the three groups. The harvested oocytes or embryos, cleavage rate, good quality embryo rate, and blastocyst production rate were counted and calculated, and the proliferations of ovarian surface epithelium were evaluated respectively. In the three groups, the single ovarian stimulation treatment significantly increased the mean number of ovarian oocytes or embryos (39.25±10.77 one-cell embryos/female); on the other hand, repeated gonadotropin stimulation obtained the lowest mean number (5.15± 2.81 eggs/female, <0.01). Repeated ovarian stimulation also tended to decrease normal follicles of primary follicles (66.67%) and secondary follicles (72.86%), and got the lowest cleavage rate (67.47%), lowest good quality embryo rate (2.41%), and lowest blastocyst production rate (0). The OSE cells adjacent to the antral follicles and corpus luteum (CL) in the repeated ovarian stimulated group (81.8%) had a significantly higher proliferation rate than the other groups. The proliferation rate of the OSE in the single ovarian stimulated group (56.4%) was significantly higher than that in the control group (37.5%) ( <0.01). In conclusion, single ovarian stimulation may produce more oocytes/embryos. However, repeated gonadotropin stimulation may have a negative effect on the ovarian follicular quality, the number of mature retrieved oocytes, and the embryo quality, even increasing the chance of ovarian cancer.

关键词： gonadotropin-releasing hormone ovarian reserve embryo developmental ability ovarian surface epithelium

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Test-driven verification/validation of model transformations

László LENGYEL,Hassan CHARAF

《信息与电子工程前沿（英文）》 2015年第16卷第2期页码 85-97 doi: 10.1631/FITEE.1400111

摘要： Why is it important to verify/validate model transformations? The motivation is to improve the quality of the transformations, and therefore the quality of the generated software artifacts. Verified/validated model transformations make it possible to ensure certain properties of the generated software artifacts. In this way, verification/validation methods can guarantee different requirements stated by the actual domain against the generated/modified/optimized software products. For example, a verified/validated model transformation can ensure the preservation of certain properties during the model-to-model transformation. This paper emphasizes the necessity of methods that make model transformation verified/validated, discusses the different scenarios of model transformation verification and validation, and introduces the principles of a novel test-driven method for verifying/validating model transformations. We provide a solution that makes it possible to automatically generate test input models for model transformations. Furthermore, we collect and discuss the actual open issues in the field of verification/validation of model transformations.

关键词： Graph rewriting based model transformations Verification/validation Test-driven verification

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Model validation for structural dynamics in the aero-engine design process

Chaoping ZANG, D. J. EWINS,

《能源前沿（英文）》 2009年第3卷第4期页码 480-488 doi: 10.1007/s11708-009-0043-8

摘要： A model validation technique in structural dynamics and its application in aero-engine development is introduced. The concept and the approaches of model validation based on reference data supplied from experimental tests or from supermodel simulation are discussed in detail. An aero-engine component is used as an example to demonstrate the validation using the experimental test and supermodel information, respectively. A satisfactory agreement with both approaches is achieved, and finally, a strategy of model validation for the whole engine model is introduced.

关键词： model validation aero-engine structural dynamics

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Stiffness analysis and experimental validation of robotic systems

Giuseppe CARBONE

《机械工程前沿（英文）》 2011年第6卷第2期页码 182-196 doi: 10.1007/s11465-011-0221-3

摘要：

Stiffness can be considered of primary importance in order to guarantee the successful use of any robotic system for a given task. Therefore, this paper proposes procedures for carrying out both numerical and experimental estimations of stiffness performance for multibody robotic systems. The proposed numerical procedure is based on models with lumped parameters for deriving the Cartesian stiffness matrix. Stiffness performance indices are also proposed for comparing stiffness performance. Then, an experimental procedure for the evaluation stiffness performance is proposed as based on a new measuring system named as Milli-CATRASYS (Milli Cassino Tracking System) and on a trilateration technique. Cases of study are reported to show the soundness and engineering feasibility of both the proposed numerical formulation for stiffness analysis and experimental validation of stiffness performance.

关键词： robotics stiffness performance numerical and experimental estimations

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Innate immune checkpoint Siglec10 in cancers: mining of comprehensive omics data and validation in patient

《医学前沿（英文）》 2022年第16卷第4期页码 596-609 doi: 10.1007/s11684-021-0868-z

摘要： Sialic acid binding Ig-like lectin 10 (Siglec10) is a member of innate immune checkpoints that inhibits the activation of immune cells through the interaction with its ligand CD24 on tumor cells. Here, by analyzing public databases containing 64 517 patients of 33 cancer types, we found that the expression of Siglec10 was altered in 18 types of cancers and was associated with the clinical outcomes of 11 cancer types. In particular, Siglec10 was upregulated in patients with kidney renal clear cell carcinoma (KIRC) and was inversely associated with the prognosis of the patients. In 131 KIRC patients of our settings, Siglec10 was elevated in the tumor tissues of 83 (63.4%) patients compared with that in their counterpart normal kidney tissues. Moreover, higher level of Siglec10 was associated with advanced disease (stages III and IV) and worse prognosis. Silencing of CD24 in KIRC cells significantly increased the number of Siglec10-expressing macrophages phagocytosing KIRC cells. In addition, luciferase activity assays suggested that Siglec10 was a potential target of the transcription factors c-FOS and GATA1, which were identified by data mining. These results demonstrate that Siglec10 may have important oncogenic functions in KIRC, and represents a novel target for the development of immunotherapies.

关键词： innate immune checkpoint Siglec10 kidney renal clear cell carcinoma

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Model validation and application

Rongrong ZHANG,Chesheng ZHAN,Xiaomeng SONG,Baolin LIU

《环境科学与工程前沿（英文）》 2015年第9卷第6期页码 1025-1035 doi: 10.1007/s11783-014-0655-z

摘要： Part I of this study develops an enhanced environmental multimedia modeling system (EMMS) based on fuzzy-set approach. Once the model development is complete, the composite module and the entire modeling system need to be tested and validated to ensure that the model can simulate natural phenomena with reasonable and reliable accuracy. The developed EMMS is first tested in a complete case study. And then verification results are conducted to compare with extensively researched literature data. In the third step, the data from an experimental landfill site is used for a pilot-scale validation. The comparisons between EMMS outputs and the literature data indicate that the EMMS can perform accurate modeling simulation. The modules of EMMS could support the entire environmental multimedia modeling system. Further field-scale validation is finished. The results are satisfactory. Most of the modeling yields closely match the monitoring data collected from sites. In addition, with the aid of fuzzy-set approach, EMMS can be a reliable and powerful tool to address the complex environmental multimedia pollution problems and provide an extensive support for decision makers in managing the contaminated environmental systems.

关键词： environmental multimedia modelling system fuzzy-set approach application model validation uncertainty analysis

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Water pumping analysis and experimental validation of beach well infiltration intake system in a seawater

Huan ZHANG,Shu LIU,Xuejing ZHENG,Gaofeng CHEN

《能源前沿（英文）》 2015年第9卷第3期页码 335-342 doi: 10.1007/s11708-015-0365-7

摘要： Based on energy conservation equation and Darcy’s law, a model of beach well infiltration intake system applied in a seawater source heat pump system was established. The model consists of the seawater seepage and the heat transfer process. A porous medium model in a software named FLUENT was applied to simulate the seepage and the heat transfer process. This model was also validated by field experiment conducted on the seashore in Tianjin, China. The maximum relative error between simulation results and experimental results was 2.1% (less than 5%), which was acceptable in engineering application. The porosity and coefficient of thermal conductivity of the aquifer soil were determined to be 0.49 W/(m·K) and 1.46 W/(m·K), respectively in the simulation. In addition, the influencing factors of pumping water of beach well were also analyzed. The pumping water was found to increase when the distance between the beach well and the impervious boundary becomes longer, when the distance between the beach well and the supplying water source shortens, when the diameter of the beach well enlarges, and the drawdown enlarges.

关键词： water pumping analysis experimental validation infiltration intake system seawater source heat pump

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Reliability prediction and its validation for nuclear power units in service

Jinyuan SHI,Yong WANG

《能源前沿（英文）》 2016年第10卷第4期页码 479-488 doi: 10.1007/s11708-016-0425-7

摘要： In this paper a novel method for reliability prediction and validation of nuclear power units in service is proposed. The equivalent availability factor is used to measure the reliability, and the equivalent availability factor deducting planed outage hours from period hours and maintenance factor are used for the measurement of inherent reliability. By statistical analysis of historical reliability data, the statistical maintenance factor and the undetermined parameter in its numerical model can be determined. The numerical model based on the maintenance factor predicts the equivalent availability factor deducting planed outage hours from period hours, and the planed outage factor can be obtained by using the planned maintenance days. Using these factors, the equivalent availability factor of nuclear power units in the following 3 years can be obtained. Besides, the equivalent availability factor can be predicted by using the historical statistics of planed outage factor and the predicted equivalent availability factor deducting planed outage hours from period hours. The accuracy of the reliability prediction can be evaluated according to the comparison between the predicted and statistical equivalent availability factors. Furthermore, the reliability prediction method is validated using the nuclear power units in North American Electric Reliability Council (NERC) and China. It is found that the relative errors of the predicted equivalent availability factors for nuclear power units of NERC and China are in the range of –2.16% to 5.23% and –2.15% to 3.71%, respectively. The method proposed can effectively predict the reliability index in the following 3 years, thus providing effective reliability management and maintenance optimization methods for nuclear power units.

关键词： nuclear power units in service reliability reliability prediction equivalent availability factors

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Assessment and validation of liquid breakup models for high-pressure dense diesel sprays

Yi REN,Xianguo LI

《能源前沿（英文）》 2016年第10卷第2期页码 164-175 doi: 10.1007/s11708-016-0407-9

摘要： Liquid breakup in fuel spray and atomization significantly affects the consequent mixture formation, combustion behavior, and emission formation processes in a direct injection diesel engine. In this paper, different models for liquid breakup processes in high-pressure dense diesel sprays and its impact on multi-dimensional diesel engine simulation have been evaluated against experimental observations, along with the influence of the liquid breakup models and the sensitivity of model parameters on diesel sprays and diesel engine simulations. It is found that the modified Kelvin-Helmholtz (KH)–Rayleigh-Taylor (RT) breakup model gives the most reasonable predicted results in both engine simulation and high-pressure diesel spray simulation. For the standard KH-RT model, the model constant for the breakup length has a significant effect on the predictability of the model, and a fixed value of the constant cannot provide a satisfactory result for different operation conditions. The Taylor-analogy-breakup (TAB) based models and the RT model do not provide reasonable predictions for the characteristics of high-pressure sprays and simulated engine performance and emissions.

关键词： breakup model diesel engine high-pressure injection simulations

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Experimental and computational validation of a scaled train tunnel model using modal analysis

Janice B. D’SOUZA, Sangarapillai KANAPATHIPILLAI

《机械工程前沿（英文）》 2013年第8卷第4期页码 420-428 doi: 10.1007/s11465-013-0281-7

摘要：

Acoustic engineers are faced with the challenge of minimising reverberation time in their designs so as to contribute to the health and well-being of those traveling by train and those on the platforms. Although the problem is easy to identify, it is not as simple to solve. The acoustical environment of a train tunnel is complex, with a variety of noise contributing factors such as train announcements, speech of commuters, ventilation systems, electrical equipment and wheel and rail noise. As a result, there is some difficulty in modeling the complete acoustic environment with computational or acoustic first principles. In this study, an experimental rig was constructed to model the acoustic behavior within a tunnel. The modal properties for the 300 Hz to 1500 Hz range, including resonances and mode shapes were identified and were shown to successfully correspond to theoretical results and a computational model created in COMSOL using Finite Element Analysis.

关键词： reverberation time acoustic environment modal properties resonances

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Validation of

Youfen Xu, Zong Li, Ruyin Liu, Hongxia Liang, Zhisheng Yu, Hongxun Zhang

《环境科学与工程前沿（英文）》 2020年第14卷第4期 doi: 10.1007/s11783-020-1246-9

摘要： Abstract • Pig feces is the predominant excrement produced by animal husbandry in China. • The PF, Pig-1-BacTaqMan, and Pig-2-BacTaqMan MST assays showed better performance. • The pig-specific MST assays can contribute to managing the pig fecal pollution. In China, pig feces is the predominant source of excrement produced by animal husbandry. Improper use or direct discharge of pig feces can result in contamination of natural water systems. Microbial source tracking (MST) technology can identify the sources of fecal pollution in environmental water, and contribute to the management of pig fecal pollution by local environmental protection agencies. However, the accuracy of such assays can be context-dependent, and they have not been comprehensively evaluated under Chinese conditions. We aimed to compare the performance of five previously reported pig-specific MST assays (PF, Pig-Bac1SYBR, Pig-Bac2SYBR, Pig-1-BacTaqMan, and Pig-2-BacTaqMan, which are based on Bacteroidales 16S rRNA gene markers) and apply them in two rivers of North China. We collected a total of 173 fecal samples from pigs, cows, goats, chickens, humans, and horses across China. The PF assay optimized in this study showed outstanding qualitative performance and achieved 100% specificity and sensitivity. However, the two SYBR green qPCR assays (Pig-Bac1SYBR and Pig-Bac2SYBR) cross-reacted with most non-pig fecal samples. In contrast, both the Pig-1-BacTaqMan and Pig-2-BacTaqMan assays gave 100% specificity and sensitivity. Of these, the Pig-2-BacTaqMan assay showed higher reproducibility. Our results regarding the specificity of these pig-specific MST assays differ from those reported in Thailand, Japan, and America. Using the PF and Pig-2-BacTaqMan assays, a field test comparing the levels of pig fecal pollution in rivers near a pig farm before and after comprehensive environmental pollution governance indicated that pig fecal pollution was effectively controlled at this location.

关键词： Microbial source tracking Pig fecal pollution 16S rRNA gene markers Pig-specific Bacteroidales